Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.
نویسندگان
چکیده
Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.
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ورودعنوان ژورنال:
- Nucleic acids research
دوره 12 3 شماره
صفحات -
تاریخ انتشار 1984